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This paper presents JOSHA’s curated synthesis of recent scientific, technological, and socio-political articles offering readers a comprehensive overview of key debates and emerging insights across disciplines. Topics range from biological aging patterns, data privacy risks in the context of genetic information and corporate bankruptcy, and the socio-cultural framing of large AI models, to policy-driven tensions between science and governance. Additionally, the collection explores challenges in fostering deep-tech entrepreneurship among PhDs, novel immunological findings on food tolerance, and reflections on societal dynamics in Germany. The compilation also includes critical analysis of artificial intelligence's role in education, law, and academic institutions, as well as discussions on AI's potential in countering misinformation.

The Brazilian educational scenario is marked by research focused on the different agents that comprise it. Due to this historical-cultural heritage, “male” teachers who work professionally in Early Childhood Education face unique difficulties, such as the peculiarity in choosing a profession, the association with pedophilia, questions about sexual orientation, looks of distrust and prejudice. That said, the question is: how can the perspective of the psychologist based on autoethnographic analysis contribute to new achievements in the performance of a “male” teacher in Early Childhood Education? This article aims to deepen the analysis and understanding of the subjectivity regarding the psychologist’s perspective on an autoethnography that permeates this “male” teacher. The relevance of this study lies in the attempt to fill epistemological gaps and advance the scientific literature, especially in the understanding of Michel Foucault’s subjectivation.

Dear josha-journal readers, A warm welcome back to the latest edition of JOSHA, May 2025. We once again have a wealth of exciting contributions. We wish all readers an enjoyable read!

Introduction: Congenital Pulmonary Airway Malformation (CPAM) is a rare fetal lung anomaly resulting from abnormal pulmonary development. It is typically detected during prenatal ultrasounds and classified into five types based on cyst size and histological characteristics. Type 2 CPAM presents as multiple small cysts (<2 cm) and is often associated with a favorable prognosis when hydrops is absent. Discussion: This case involves a 36-year-old pregnant woman whose fetus was diagnosed with type 2 CPAM at 19 weeks. Despite delayed referral, the fetus showed no signs of hydrops or hemodynamic compromise. Corticosteroid therapy with betamethasone was administered at 31 weeks, and follow-up imaging revealed complete regression of the lesion. The low CPAM volume ratio (CVR 0.12) and absence of complications supported conservative management.

Kabuki syndrome (KS) is a rare genetic disorder caused by mutations in the KMT2D or KDM6A genes, affecting development and leading to multiple malformations. Diagnosis is usually postnatal, although prenatal detection through ultrasound and genetic testing can be key. A case was presented in Santander, Colombia, where a male fetus exhibited anomalies on ultrasound, including cleft lip and palate, complex heart disease, and skeletal malformations. Due to the suspicion of KS, a chromosomal microarray was performed, confirming a mutation in KDM6A. The postnatal diagnosis corroborated the phenotypic characteristics of the syndrome. This case highlights the importance of prenatal ultrasound in detecting suggestive signs of KS and guiding confirmatory genetic studies. It is the first reported case with KDM6A in the region, expanding knowledge about KS in Latin America. Early identification enables optimized neonatal management and improved prognosis.

To enhance communication, JOSHA presents a curated selection of articles chosen by its editors. This edition highlights innovative research, including EVOLVEpro, a protein engineering method that integrates protein language models and active learning to optimize enzymes, antibodies, and gene-editing tools; bacterial-MERFISH, a technique for high-resolution bacterial transcriptomics that provides new insights into bacterial behavior and interactions; a reflective piece on the impact of casual academic interactions in overcoming professional hierarchies; and a study on the differential proliferation of plasma cells in antibody affinity maturation, emphasizing the role of IL-21 in promoting high-affinity antibody responses. These studies contribute significantly to advancements in biotechnology, microbiology, and immunology.

To facilitate and enhance communication, JOSHA presents a curated selection of research summaries spanning critical scientific, technological, and societal developments. This edition covers the environmental and sovereignty risks posed by a new U.S. military base in the Galápagos Islands, the rise of tiny machine learning (tinyML) as a low-cost AI solution in the Global South, and Microsoft’s claim of creating a new state of matter to advance quantum computing. Also featured is an exploration of how stand-up comedy helped a researcher overcome stage fright and improve scientific communication. Finally, an editorial examines the impact of President Trump’s second-term policies on science, including deep funding cuts, restrictions on research, and the rollback of global collaborations. Explore the full articles for a deeper understanding of these important topics.

Dear josha-journal readers, In what kind of world do we want to live in? In a world of walls and influence by government agencies? A world of bias and doubt towards others? Or in a world of exchange between countries, people and, in particular, scientific exchange? We at josha-journal strongly advocate the second answer. And so, in its twelfth year of existence, the journal should be a forum for all those who wish to further this exchange. Only free scientific research, the removal of boundaries and mutual trust will take us further. And so we work as a team with our slogan “Better together - together better”!

For two years, EMMA Association’s (Hungary) Humanitarian Programme field workers have been helping Roma refugee women and girls from Ukraine to access services related to sexual and reproductive health (SRH). They provided complex psychosocial support to these women, also support in navigating the healthcare system and specific physical accompaniment. This publication summarizes the results of our qualitative research with twenty-one Roma refugee women. In all cases, we interviewed women who had an existing trustful relationship with EMMA field workers. Although we focused on SRH related experiences of women, to get a broader picture of their situation, we also addressed other questions relevant to refugee women, such as the circumstances of their arrival in the country, the housing difficulties, their livelihoods, their attitude towards womanhood and their plans for the future.

Dandy-Walker Malformation (DWM) is a rare congenital brain disorder affecting the cerebellum and posterior fossa, occurring in 1 in 35,000 births. It is characterized by agenesis of the cerebellar vermis, fourth ventricle dilation, and an enlarged posterior fossa. Genetic factors, chromosomal abnormalities, and infections like rubella, CMV, and toxoplasmosis contribute to its etiology. This case describes a 16-year-old pregnant woman whose fetus was diagnosed with Dandy- Walker malformation (DWM) at 23.3 weeks. Prenatal findings included severe intrauterine growth restriction, absence of the cerebellar vermis, dysgenesis of the corpus callosum, and cardiac abnormalities. PCR confirmed Toxoplasma gondii infection. Despite treatment, fetal death occurred at 24 weeks. Karyotype analysis ruled out chromosomal abnormalities, suggesting a rare infectious etiology rather than a genetic cause.